Mike Macdonald shut down the San Francisco 49ers last season, and now looks to do the same with the Seattle Seahawks.

We’re now five weeks into the NFL season, and there are far more questions than answers for the San Francisco 49ers.

Brock Purdy had two costly interceptions against the Cardinals, resulting in a disappointing one-point loss for the 49ers.

But the first series — a two-play, 72-yard touchdown drive, saw Campbell burned on a chunk-yard pass and then a 50-yard ...

Chad Ryland didn't have a job just a week ago, but he kicked three field goals for the Cardinals, including the game winner ...

What's the Arizona Cardinals vs San Francisco 49ers score? Follow our live game updates for the latest news, analysis from ...

Driving into the red zone hasn’t been a problem early this season for the San Francisco 49ers, who have gotten past the ...

The 49ers just blew another 10-point fourth quarter lead and lost 24-23 to the Arizona Cardinals. Now the 49ers are 2-3. Here are their grades fo ...

Kyler Murray had a long touchdown run in the first quarter and rallied Arizona with two fourth-quarter scoring drives in the ...

Brock Purdy has changed. When he first became the 49ers starting quarterback, he was a game manager. A ball distrubtor. He took what the defense ...

There have been several positive surprises over the first five weeks of the 2024 NFL season, with the Minnesota Vikings and ...

Down several players on defense, the Seahawks will have their work cut out for them in stopping San Francisco quarterback ...