Rookie safety Malik Mustapha isn't quite sure what to expect when his San Francisco 49ers travel to Seattle this week to face ...

The San Francisco 49ers received good news on George Kittle's injury status ahead of Thursday's Seattle Seahawks game.

Justin Jefferson’s bye week. Four NFL teams were off last week, but Week 6 is the first one with significant bye consequences ...

Jimmie Kaylor shares his Week 6 NFL DFS picks, sleepers, rankings, values and player pool for Seahawks vs. 49ers on TNF ...

San Francisco 49ers tight end George Kittle speaks to reporters Tuesday and discusses his team’s red-zone struggles and its ...

(AP) — Driving into the red zone hasn’t been a problem early this season for the San Francisco 49ers, who have gotten past the opponent ... threw late and slightly off-target to tight end George ...

San Francisco 49ers wide receiver Deebo Samuel Sr. faded into the background during a 24-23 home upset at the hands of the Arizona Cardinals on Sunday. Samuel Sr. saw three targets and caught just one ...

San Francisco 49ers head coach Kyle Shanahan spoke to reporters ahead of Wednesday's practice as the team prepares for its ...

There's bad news for fantasy owners regarding George Kittle ... NFL: New York Jets at San Francisco 49ers - Source: Imagn CBS revealed that Kittle's absence was due to cramps.

SANTA CLARA, Calif. (AP) — Brock Purdy threw a touchdown pass, Fred Warner returned an interception for a score and the San Francisco 49ers snapped a two-game skid by beating the New England Patriots ...

The San Francisco fans didn't get to see their influential tight end against the Los Angeles Rams in Week 3, but hopes have ...