Now, SportsLine's NFL DFS optimizer has turned its attention to Sunday's 2024 NFL Week 5 schedule and just locked in its top daily Fantasy football lineups. You can only see its optimal lineups at SportsLine.

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This week's DFS slate includes a contest between the Bills and the Texans. The top DFS options from these two teams can be found below, with their salaries included. Catch every NFL touchdown with NFL RedZone on Fubo. Get in the game and sign up for FanDuel Fantasy today. Use our link to start playing daily fantasy.

The Packers play the Rams, who have one of the worst defenses to begin the 2024 NFL season. The Rams have the second-worst scoring defense (28.8 points per game) while allowing the second-most yards (385.

A good way to start your weekly homework for DFS (daily fantasy sports) play is to analyze the early Vegas odds around Week 5. These guys have a long history of making money off of setting the right game spread and points scored.

On Sunday, October 6, 2024, the San Francisco 49ers and Arizona Cardinals will clash at Levi's Stadium. Keep reading for DFS options to consider for this matchup.

Player analysis and projections can be found in our Start/Bench Tool customized to your myHuddle league scoring and rosters. All… You must be a Huddle Member to continue reading this selection. Members enjoy full access to all our premium features, including cheat sheets, sleepers, player rankings, draft tools, and more. Don't be left in the dark!

Week 5 of Thursday Night Football features an NFC South matchup between the Atlanta Falcons (-1.5, 43.5) and Tampa Bay Buccaneers at 8:15 p.m.