Rookie safety Malik Mustapha isn't quite sure what to expect when his San Francisco 49ers travel to Seattle this week to face ...

The San Francisco 49ers received good news on George Kittle's injury status ahead of Thursday's Seattle Seahawks game.

Justin Jefferson’s bye week. Four NFL teams were off last week, but Week 6 is the first one with significant bye consequences ...

Jimmie Kaylor shares his Week 6 NFL DFS picks, sleepers, rankings, values and player pool for Seahawks vs. 49ers on TNF ...

San Francisco 49ers tight end George Kittle speaks to reporters Tuesday and discusses his team’s red-zone struggles and its ...

The 49ers estimated linebacker George Kittle (ribs) and linebacker Fred Warner (ankle) as limited again. They held a ...

(AP) — Driving into the red zone hasn’t been a problem early this season for the San Francisco 49ers, who have gotten past the opponent ... threw late and slightly off-target to tight end George ...

San Francisco 49ers wide receiver Deebo Samuel Sr. faded into the background during a 24-23 home upset at the hands of the Arizona Cardinals on Sunday. Samuel Sr. saw three targets and caught just one ...

Brock Purdy threw two interceptions in the second half, Jordan Mason lost a fumble in the red zone and San Francisco allowed Kyler Murray and the Arizona Cardinals to drive for two fourth-quarter ...

The San Francisco 49ers got some needed reinforcements for the defensive interior but will wait at least another week to get first-round rookie receiver Ricky Pearsall back at practice. This was the f ...